The LSD-25
In 1938, Dr. Albert Hoffman synthesized a bunch of compounds based on the fungus “ergot.” His hope: to stimulate the human circulatory system. The 25th compound - LSD-25 - didn’t seem to have much effect on lab animals, so he chucked it. But 5 years later, on April 19th, 1943, Hoffman was gripped by what he called a “peculiar presentiment,” and made another batch…which he sampled. We commemorate the ensuing bike trip with this drink laced with entirely legal acid and fungi.
“The LSD-25,” as invented for the DPD by Daniel Hyatt, bar manager at Alembic in San Francisco:
Into champagne flute, place:
- 4 drops white balsamic vinegar
- 1 drop truffle oil
Then slowly pour in the following — over the back of a spoon — to create separate layers:
- 3/4 oz. crème de Cassis
- 1/2 oz. Campari
- 1/2 oz. Absinthe
Finally, slowly pour in:
- 3 oz. chilled sparkling wine (Gruet demi-sec, or slightly off-dry Prosecco)
Trip out on the colors as the liquors mix. Toss in a twist of lemon peel. Sip. Wait at least an hour before attempting to operate a bicycle.

